The university was opened in 1992 on the wave of major political and economic transformations in the country. It was at that time that the academician of the Academy of Sciences of the Republic of Kazakhstan, a member of the International Association of Surgeons, the People's Hero of Kazakhstan – Mukhtar Aliyevich Aliyev, together with Professor K.M. Maskeyev and Associate Professors V.S. Golubchenko and O.A. Panova, founded one of the first private universities in the CIS – then the Kazakh Medical Institute.

During this time, the university has gained a reputation as the leading medical university in the country. It has trained tens of thousands of specialists who are now successfully working in the healthcare sector.

Academician Aliyev M.A. laid the foundation for high-quality medical education that meets the highest standards, emphasizing practical training for future doctors. To achieve this, the university has an impressive scientific and clinical base, including over a hundred leading clinics in the country.

The basic education at the Kazakh-Russian Medical University includes 6 specialties: Medicine, Dentistry, Public Health, Pharmacy, Nursing, and Medical and Preventive Care. Postgraduate education programs provide in-depth knowledge in more than 20 residency specialties, as well as advanced training and professional retraining for medical and pharmaceutical professionals.

The educational process is implemented by world-renowned doctors and prominent Kazakhstani and foreign scientists. World-class scientists and leaders of international healthcare are honorary professors at the Kazakh-Russian Medical University, such as: Sir Rodney Errie Lawrence Williams – Governor-General of Antigua and Barbuda, Vedjdet Oz – Professor at Istanbul University, and others.

The university offers a unique course called "Artistic Anatomy" designed for students who seek to understand the anatomical foundations of the human body in order to create realistic paintings. It combines theoretical lectures with practical exercises aimed at consolidating knowledge and developing skills in depicting anatomical structures.
The course is taught by experienced professors, artists, and anatomists who possess a wealth of knowledge and years of experience.

The Kazakh-Russian Medical University is building its own medical center. The university clinic will become an important part of the educational process. Here, students will gain invaluable experience by working under the guidance of experienced doctors and specialists. They will have the opportunity to apply their theoretical knowledge in practice, observe patients, and participate in diagnosis and treatment.

The Kazakh-Russian Medical University is the founder of transport medicine and disaster medicine in Kazakhstan. In 2008, at the initiative of the Rector, Professor Dzhainakbayev N.T., with the support of charitable and public funds, the first Mobile Medical Complexes were created to provide medical and sanitary assistance to the rural population of Kazakhstan.

During this time, we have developed and implemented technologies for creating mobile medical complexes, from polyclinics to modern hemodialysis centers, which are in demand all over the world, both during normal times and in emergency situations. Since 2008, our faculty members and students have actively participated in real-life emergency response missions.